![]() ![]() The published data on COVID-19 in children primarily comes from China, USA and Europe. There is a differential susceptibility of persons towards COVID-19 infection in various blood groups as the human blood type is noted to be a biomarker of susceptibility of COVID-19 infection and the people with blood group A may need particularly augmented personal protection to reduce the chance of infection and to receive more cautious surveillance and aggressive management. ![]() Researches on COVID-19 patients described a relationship between ABO blood groups and severity of viral infection. ![]() 1 Few children present with hyper-inflammatory condition called as multisystem inflammatory syndrome in children (MIS-C) or Kawasaki disease (KD) like illness. COVID-19 is generally a milder disease in children, but severe cases have been reported in the literature. The World Health Organisation (WHO) declared COVID‐19 as a Global health emergency and a pandemic disease on 11 th March, 2020. Key Words: Coronavirus disease 2019, ABO blood groups, Children, Severity, Outcome.Ĭorona virus disease 2019 (COVID-19), caused by a novel coronavirus (SARS-CoV-2), resulted in global pandemic after a severe outbreak in China. COVID-19 in children had generally a good outcome, but children with blood group A were more susceptible to severe/critical disease. Blood group A was significantly associated with severe and critical disease (p=0.030). Among all patients, 24 (36.4%) had some underlying comorbidity. Majority of children had mild to moderate illness 38 (57.6%), while 23 (34.8%) had severe or critical disease. Out of 66 children, 45 (68.2%) were COVID-19 and 21 (31.8%) MIS-C/KD temporally associated with SARS-C0V-2. It included all laboratory-confirmed cases of COVID-19 and post-COVID multisystem inflammatory syndrome in children (MIS-C)/ Kawasaki disease (KD) like illness, admitted from March to September, 2020 to The Children’s Hospital, Lahore. The objective of this study was to find out the association of ABO blood groups with the severity and outcome of corona virus disease 2019 (COVID-19) in children. ![]()
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